Tysabri works on the cells that cause inflammation and damage; it has stopped MS in its tracks for me and given me better control of my body.
The active ingredient of Tysabri is Natalizumab, a protein similar to your own antibodies. It stops the immune cells that can cause inflammation from going into your brain. This reduces the nerve damage caused by MS. Thus slowing the progression of MS.
1. With MS, the immune cells (white blood cells) that can cause inflammation across the blood brain barrier (BBB) from the circulation and enter the central nervous system. Tysabri acts like the border agency stopping illegal immigration of the white blood cells
2. Once in the central nervous system the white blood cells may become activated and begin to target the nerve tissue. Because Tysabri stops the migration of white cells into the central nervous system, it helps to slow this destructive process.
Does it work?
Based on clinical trials Tysabri reduced the progression of the disabling effects of MS by over 60%. Tysabri decreased the number of attacks by over 80%.
For me two years on Tysabri and I’ve not had a relapse. I still have good days and bad days but I’m rarely severely ill like I was before beginning this medication.
Very occasionally some patients may have hypersensitivity or an allergic reaction to Tysabri. These occur during the infusion or shortly afterwards. Rare cases of liver problems but there have been cases of a brain infection called PML that could lead to death. Of course, like all medications, talk to your doctor before taking.
Are you on Tysabri? Have you experienced any side effects? Please share your experience with Tysabri.