A new study is showing the gut bacteria may control cells in the brain that create inflammation and neurogeneration show in those with multiple sclerosis. This demonstrates food is actually shown to affect those with the chronic disease.
According to the Multiple Sclerosis Foundation, “Investigators at Brigham and Women’s Hospital wanted to know how gut microbiome and brain inflammation are linked, and how diet and microbial products influence this connection. They performed analyses on astrocytes – star-shaped cells that reside in the brain and spinal cord – in a mouse model of MS, identifying a molecular pathway involved in inflammation. They found that molecules derived from dietary tryptophan act on this pathway, and that when more of these molecules are present, astrocytes were able to limit brain inflammation. In blood samples from MS patients, the team found decreased levels of these tryptophan-derived molecules.”
Francisco Quintana, Ph.D., one of the study’s authors states. “What we eat influences the ability of bacteria in our gut to produce small molecules, some of which are capable of traveling all the way to the brain. This opens up an area that’s largely been unknown until now: how the gut controls brain inflammation.”
The research team plans to investigate the role of diet in future studies in hopes it can be translated into future therapies and help to diagnose and detect advancement of multiple sclerosis.
Are you hopeful? Does your diet affect your MS?